Atypical case of acute kidney injury due to clindamycin use in a child
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Description
ABSTRACT
Acute kidney injury (AKI) is commonly caused by medications including, but not limited to,
aminoglycosides, cephalosporins, penicillins, trimethoprim-sulfamethoxazole, and amphotericin.
Among pediatric patients, clindamycin has been widely used to treat skin and soft-tissue infections,
abscesses, osteomyelitis, and aspiration pneumonia.1,2 Clindamycin is well-known to cause diarrhea,
Clostridioides difficile (C. diff) infection, hypersensitivity reactions, and gastrointestinal upset.3 However,
AKI is not a commonly associated side effect of clindamycin, despite its widespread use among pediatric
patients.3,4 A review of the literature reveals no previous reports of AKI caused by clindamycin in children.
This case report presents a case of a 14-year-old female with extensive cellulitis who developed AKI
most likely from clindamycin.
Subjects
Affiliations
- California Health Sciences University, College of Osteopathic Medicine, Clovis, CA
- Valley Children’s Hospital, Department of Pediatric Hospital Medicine, Madera, CA