CHSU Discovery

Obesity and Aging

Article

The obesity epidemic in aging populations poses significant public health concerns for greater morbidity and mortality risk. Age-related increased adiposity is multifactorial and often associated with reduced lean body mass. The criteria used to def…

Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring

Article

ObjectivesPrenatal stress (PS) can adversely affect cognitive and psychological functions in the offspring. This study aimed to determine the effect of PS and extremely low-frequency electromagnetic field (ELF-EMF) on spatial memory, serum corticost…

Stem cell treatment improves post stroke neurological outcomes: a comparative study in male and female rats.

Article

BACKGROUND AND PURPOSEThe therapeutic potential of different stem cells for ischaemic stroke treatment is intriguing and somewhat controversial. Recent results from our laboratory have demonstrated the potential benefits of human umbilical cord bloo…

Acute Acalculous Cholecystitis in a Patient With Pancolitis: A Case Report

Article

Salmonella is an infectious bacterial organism found in many food products. In this case, there is an investigation into salmonella infection leading to acute acalculous cholecystitis (AAC). Pancolitis, although mostly caused by ulcerative colitis, …

Services and staffing practices in academic health sciences libraries serving college of osteopathic medicine programs: a mixed methods study

Article

OBJECTIVEThis study describes and assesses services, staffing practices, and trends in academic health sciences libraries that serve accredited college of osteopathic medicine (COM) programs in the United States.METHODSThe study was conducted in thr…

Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers

Article

BACKGROUNDQuercetin (QCT), a naturally occurring flavonoid has a wide array of pharmacological properties such as anticancer, antioxidant and anti-inflammatory activities. QCT has low solubility in water and poor bioavailability, which limited its u…

Intranasal AdipoRon mitigates motor and cognitive deficits in hemiparkinsonian rats through neuroprotective mechanisms against oxidative stress and synaptic dysfunction

Article

While motor symptoms are the most well-known manifestation of Parkinson's disease (PD), patients may also suffer from non-motor signs like cognitive impairments. The adiponectin receptor agonist AdipoRon (Adipo) has shown neuroprotective effects in …

Benefits and Risks of Medications Used in the Management of Hypotension: A Review

Article

This comprehensive literature review addresses the scarcity and limited study of hypotension treatments compared to abundant antihypertensive drugs. Hypotension, categorized as absolute, relative, or orthostatic, has diverse causes. This review expl…

A Retrospective Study of Outcomes in a Rural Pediatric Population Treated for Venous Insufficiency

Article

BACKGROUNDEndovascular radiofrequency ablation (RFA) and Endovascular Laser Ablation (EVLA) are minimally invasive methods to safely treat symptomatic varicose veins in pediatric patients. This research aimed to review the management of pediatric pa…

Breathing life into learning about air quality: developing and implementing environmental health outreach with high school students

Article

Background: The San Joaquin Valley (SJV) is comprised of diverse populations that cumulatively are medically underserved and experience significant air pollution. The SVJ regularly has poor air quality and does not meet the state and federal a…

Comparison of endoscopic thyroidectomy by complete areola approach and conventional open surgery in the treatment of differentiated thyroid carcinoma: A retrospective study and meta-analysis

Article

BackgroundThe feasibility of endoscopic thyroidectomy by complete areola approach (ETCA) remains controversial. This study was conducted by combining our clinical data with the data obtained from a systematic review literature search to examine the …

Parental refusal of childhood vaccines is a growing public health concern. Numerous reasons exist for this refusal, including religious, personal, and philosophical beliefs, and safety concerns. However, parental refusal of childhood vaccines …

Epithelial-to-Pericyte Transition in Cancer

Article

During epithelial-to-mesenchymal transition (EMT), cells lose epithelial characteristics and acquire mesenchymal properties. These two processes are genetically separable and governed by distinct transcriptional programs, rendering the EMT outputs h…

The effects of age, genotype and diet on hippocampal subfield iron dysregulation and Alzheimer's disease biomarkers in an ApoE mouse model

Article

Current theories regarding accumulation of Alzheimer's disease-related deposits of abnormal intra- and extracellular proteins include reactions to inflammation and mitochondrial dysfunction. In this study, we explored whether age, genotype and infla…

Incorporating ACPE Standards in a Holistic Approach to School Operations and Accreditation

Article

Auburn University Harrison School of Pharmacy (AUHSOP) implemented a comprehensive, holistic process of continuous quality improvement (CQI) for its program using the Accreditation Council for Pharmacy Education's (ACPE) Accreditation Standards as t…

Critical Appraisal of Biomedical Literature With a Succinct Journal Club Template: The ROOTs Format

Article

Journal clubs are a valuable tool to assist pharmacists in the evaluation of biomedical literature and to promote adoption of evidence-based practices. The concise ROOTs (relevance, observe validity, obtain clinically significant results, and transl…

Understanding Public Perception of Over-the-Counter Hearing Aids: A Sentiment and Thematic Analysis of Consumer Reviews

Article

ObjectiveTo analyze public perceptions of over-the-counter (OTC) hearing aids through sentiment and thematic analysis of online consumer reviews and their changes over time.Study DesignSentiment and thematic analysis.SettingOnline reviews from third…

Recent Advances in the Management of Dyslipidemia: A Systematic Review

Article

Dyslipidemia refers to abnormal levels of lipids in the bloodstream, typically exhibiting an increased pattern. Total cholesterol, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), and triglycerides (TGs) are…