CHSU Discovery

Therapeutic potential of adipose stem cell-derived conditioned medium against pulmonary hypertension and lung fibrosis

Article

BACKGROUND AND PURPOSEPulmonary hypertension (PH) and pulmonary fibrosis (PF) are life threatening cardiopulmonary diseases. Existing pharmacological interventions have failed to improve clinical outcomes or reduce disease-associated mortality. Emer…

Transforming Prescription Opioid Practices in Primary Care With Change Theory

Article

The opioid epidemic continues to be an ongoing public health crisis. Many primary health care providers aptly serve as the gatekeeper to opioid prescriptions. The opioid epidemic has challenged the primary care profession whilst many of these provid…

Blast-Related Mild Traumatic Brain Injury: Case Report Highlighting the Long-Term Neurocognitive Sequelae Following Blast Exposure in Veterans.

Article

Traumatic brain injury (TBI) remains a significant public health concern, particularly among military service members exposed to blast-related trauma. While mild TBIs often resolve within weeks, a subset of patients may experience lifelong, persiste…

Safety and Effectiveness of a Standardized Intravenous Insulin Infusion Order Set for Managing Uncontrolled Hyperglycemia Outside the Intensive Care Unit

Article

BACKGROUNDFew studies have evaluated the administration of intravenous (IV) insulin infusions for uncontrolled hyperglycemia in non-intensive care unit (ICU) patients, and there is inadequate data to guide how to appropriately administer IV insulin …

Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c)

Article

The Mycobacterium tuberculosis (Mtb) serine protease Hip1 (hydrolase important for pathogenesis; Rv2224c) promotes tuberculosis (TB) pathogenesis by impairing host immune responses through proteolysis of a protein substrate, Mtb GroEL2. The cell sur…

Tissue Augmentation Techniques in the Management of Ligamentous Knee Injuries

Article

Despite early reports of high failure rates in knee ligament repair techniques resulting in favor of reconstruction, newer advances in surgical technology have shifted the attention back to repair with the addition of various tissue augmentation tec…

National Survey Exploring Drug Screening in Pharmacy Programs

Article

Objective. To explore drug screening programs, including requirements, policies, and procedures among pharmacy programs; frequency of drug-related incidents; and types of substances misused by pharmacy students. Methods. IRB-approved web-based and p…

Nanodelivery and anticancer effect of a limonoid, nimbolide, in breast and pancreatic cancer cells

Article

INTRODUCTIONNimbolide (Nim), a limonoid obtained from the neem tree, Azadirachta indica, has several pharmacological properties, including anticancer effects in different type of cancers. No drug-delivery system has been reported for enhancing the t…

Nonopioid Pain Protocols vs. Opioid Analgesia for Postoperative Pain Control Following Arthroscopic Surgeries: A Literature Review

Article

Arthroscopic surgery is a widely used technique in orthopedic practice for treating various joint pathologies, including anterior cruciate ligament (ACL) tears, meniscal injuries, and rotator cuff tears. Arthroscopy offers a minimally invasive alter…

Enhancing nutrition and lifestyle education for healthcare professional students through an interprofessional, team-based training program

Article

BACKGROUND AND PURPOSENutrition and lifestyle modifications are effective interventions in tackling many chronic diseases, including cardiovascular diseases. However, healthcare professionals are not sufficiently trained in nutrition and lifestyle e…

Efficient and effective precepting of pharmacy students in acute and ambulatory care rotations: A Delphi expert panel study

Article

PURPOSEUsing the Delphi process, a panel of experienced preceptors achieved consensus on best practices to increase preceptor efficiency and effectiveness.METHODSThe Delphi panelists completed 3 survey rounds and a face-to-face meeting. Survey quest…

Who is the Teacher and Who is the Student? The Dual Service- and Engaged-Learning Pedagogical Model of Anatomy Academy

Article

Anatomy Academy is a simultaneous service-learning experience for preprofessional school undergraduate students and preclinical professional students acting as classroom paraprofessional teachers (Mentors), and engaged-learning experience for fourth…

Casting a New Light: A Systematic Review of 3D-Printed Casting for Non-Surgical Management of Orthopedic Injuries

Article

Traditional casting methods for fracture immobilization, such as plaster and fiberglass, have been used for decades but come with limitations, including discomfort, poor ventilation, and difficulty in application. Three-dimensional printing (3DP)…

CONTEXTPremedical preparatory programs at osteopathic medical schools that recruit students from medically underserved areas (MUAs) may promote interest in practicing osteopathic medicine in underserved or rural areas. In these programs, emphasis on…

Six practical tips to prepare for the Comprehensive Osteopathic Medical Licensing Examination (COMLEX) USA level 1

Article

Abstract Sophisticated high-stakes licensure and specialty certification maintenance examinations are educational requirements in osteopathic medicine. Passing the Comprehensive Osteopathic Medical Licensing Examination (COMLEX) USA Level 1 is one o…

Connective tissue growth factor expression hints at aggressive nature of colorectal cancer

Article

BACKGROUNDConnective tissue growth factor (CTGF) is a mediator of transforming growth factor-beta signaling and plays a key role in connective tissue remodeling, inflammatory processes and fibrosis in various illnesses including cancer.AIMTo investi…

Evidence-Based Topical Therapy for Facial Scars in Diverse Skin Types

Article

Facial trauma repair frequently results in scarring that can significantly impact psychological well-being, particularly in highly visible areas, such as the face. While topical agents provide a non-invasive means of optimizing scar outcomes, clinic…

Ten Tips for Pharmacy Faculty Members for Successfully Navigating Promotion and Tenure

Article

This paper presents 10 key tips or recommendations for successful navigation of the promotion and tenure process. The 10 key tips are: know institutional expectations, develop an action plan at least two to three years in advance; identify your bala…