CHSU Discovery

Although peer evaluations are essential to team-based learning, they can be problematic. Team activity debriefings (TAD) are advantageous because they focus on the team's problem-solving strategies and teamwork skills. Students (N = 100) who used bo…

Relevance of epithelial-to-pericyte transition in cancer

Article

The relevance of epithelial-to-mesenchymal transition (EMT) in cancer is still under debate. Recently, we reported that EMT bestows key pericyte properties on cancer cells and may thus represent epithelial-to-pericyte transition (EPT). Carcinoma cel…

INTRODUCTIONCrowdsourcing is a method of data collection with possible benefits in assessing perceptions of mental illness in a large US population.METHODSThe objective was to describe perceptions and trends of stigma surrounding mental illness in t…

Correction: A Comprehensive Review of Novel FDA-Approved Psychiatric Medications (2018-2022)

Article

[This corrects the article DOI: 10.7759/cureus.56561.].

A comprehensive review of clinical experiences and extracurricular activities for US premedical students applying to osteopathic medical schools

Article

CONTEXTThe healthcare industry faces a critical shortage of qualified physicians. To address this growing concern, medical schools nationwide are increasing their efforts to recruit and train premedical students to fill this gap. Those efforts inclu…

SAT-355 Thyrotoxicosis Associated with Leukopenia in Graves' Disease: A Case Report and Review of Medical Management

Article

Disclosure: C. Makhija: None. M. Bhalla: None. S.S. Thangwaritorn: None. Leukopenia is characterized by a low white blood cell count (WBC) and, is an uncommon manifestation of hyperthyroidism associated with Graves’ disease, affecting …

Exosomes as a therapeutic tool to promote neurorestoration and cognitive function in neurological conditions: Achieve two ends with a single effort

Article

Exosomes possess a significant role in intercellular communications. In the nervous system, various neural cells release exosomes that not only own a role in intercellular communications but also eliminate the waste of cells, maintain the myelin she…

BackgroundIschemic colitis is the most common presentation of mesenteric ischemia and is associated with significant morbidity and mortality. Coagulopathy has been associated with the development of ischemic colitis. Coronavirus disease 2019 (COVID-…

Acute Interpositional Fat Autograft Does Not Protect Against Bar Formation in Physeal Fractures

Article

BACKGROUNDLong-bone fractures in children can lead to premature physeal bar formation and growth disturbance. Bar excision has been studied, but data on prophylactic tissue interposition into physeal fractures are limited. This study used an establi…

High-fat diet-induced glucose dysregulation is independent of changes in islet ACE2 in mice

Article

While restoration of ACE2 activity in the pancreas leads to improvement of glycemia in experimental models of Type 2 diabetes, global deficiency in ACE2 disrupts β-cell function and impairs glucose tolerance in mice, demonstrating the physiological …

Blending team-based learning and game-based learning in pharmacy education.

Article

BACKGROUND AND PURPOSETeam-based learning (TBL) and game-based learning (GBL) are evidence-based active learning pedagogies. This study reports a learning experience that harnesses TBL and GBL benefits by blending both pedagogies (referred herein as…

Involvement of Neuroinflammation in the Pathogenesis of Monocrotaline-Induced Pulmonary Hypertension

Article

Pulmonary hypertension (PH) is a devastating disease and its successful treatment remains to be accomplished despite recent advances in pharmacotherapy. It has been proposed that PH be considered as a systemic disease, rather than primarily a diseas…

Metastatic Melanoma to the Orbit With Dedifferentiation: A Case Report

Article

We present the first documented case of metastatic melanoma to the orbit with dedifferentiation. A patient with a history of melanoma of the lip and other poorly differentiated carcinomas presented with both a sub-brow and an intraorbital mass. Radi…

Drug-induced pancreatitis (DIP), while not a major cause of acute pancreatitis, remains a debilitating diagnosis resulting in significant patient morbidity and mortality. The diagnosis includes first diagnosing acute pancreatitis, second ruling out …

Chatbots and Diabetes: Is There Gender Bias?

Article

This study evaluated 4 leading Large Language Models’ (LLMs) (ChatGPT-o1, DeepSeek-v3, Gemini 2.0 Flash, and Claude 3.7 Sonnet) responses to a question about Diabetic Retinopathy. Methods: The following questions were posed to the 4 LLMS: “I am a 52…

Quantifying Changes in 3D Acetabular Morphology in Normal Hips Based on the Development of Secondary Ossification Centers.

Article

BACKGROUNDAcetabular development in pediatric hips is driven by growth from the triradiate cartilage (TRC) and secondary ossification centers (SOCs) of the os pubis, os ischium, and os ilium. These SOCs appear and fuse at different ages, with sex-sp…

Modified peroxamide-based reactive oxygen species (ROS)-responsive doxorubicin prodrugs.

Article

Reactive oxygen species (ROS) plays a pivotal physiological role in intracellular signaling of any living organism. Due to the elevated levels of ROS in tumor microenvironment than normal tissues, an increasing number of ROS-responsive probes and pr…

The Associations Between Obesity and Deep Vein Thrombosis in Patients With Cardiovascular Disease: A Narrative Review

Article

This article provides an in-depth review of the relationship between obesity and deep vein thrombosis (DVT) in patients with cardiovascular disease (CVD). Our aim is to enhance understanding of the associations between obesity and DVT, particularly …

Finding balance: Offering a systematic method to explore the influence of technology on team-based learning.

Article

INTRODUCTIONTeam-based learning (TBL) is a small group active learning andragogy promoting the development of critical thinking, communication, and teamwork skills. Across higher education, the adoption of educational technology is often driven by m…