CHSU Discovery

BACKGROUND AND PURPOSEPulmonary hypertension (PH) and pulmonary fibrosis (PF) are life threatening cardiopulmonary diseases. Existing pharmacological interventions have failed to improve clinical outcomes or reduce disease-associated mortality. Emer…

Polycystic ovary syndrome (PCOS) is a common endocrine disorder that disrupts reproductive function and hormonal balance. It primarily affects reproductive-aged women and leads to physical, metabolic, and emotional challenges affecting the quality o…

BACKGROUNDHypertriglyceridemia-associated acute pancreatitis is a disease lacking a standardized management approach.OBJECTIVEThe main objective of this study was to evaluate the safety and efficacy of a continuous intravenous insulin infusion order…

BACKGROUNDNicardipine is commonly used in the management of hypertensive crises, except those involving cardiac contractility defects despite its ability to reduce afterload and pulmonary congestion. Consequently, there is limited literature evaluat…

While motor symptoms are the most well-known manifestation of Parkinson's disease (PD), patients may also suffer from non-motor signs like cognitive impairments. The adiponectin receptor agonist AdipoRon (Adipo) has shown neuroprotective effects in …

BACKGROUNDEndovascular radiofrequency ablation (RFA) and Endovascular Laser Ablation (EVLA) are minimally invasive methods to safely treat symptomatic varicose veins in pediatric patients. This research aimed to review the management of pediatric pa…

OBJECTIVEThis study describes and assesses services, staffing practices, and trends in academic health sciences libraries that serve accredited college of osteopathic medicine (COM) programs in the United States.METHODSThe study was conducted in thr…

This comprehensive literature review addresses the scarcity and limited study of hypotension treatments compared to abundant antihypertensive drugs. Hypotension, categorized as absolute, relative, or orthostatic, has diverse causes. This review expl…

BACKGROUNDQuercetin (QCT), a naturally occurring flavonoid has a wide array of pharmacological properties such as anticancer, antioxidant and anti-inflammatory activities. QCT has low solubility in water and poor bioavailability, which limited its u…

Background: The San Joaquin Valley (SJV) is comprised of diverse populations that cumulatively are medically underserved and experience significant air pollution. The SVJ regularly has poor air quality and does not meet the state and federal a…

Salmonella is an infectious bacterial organism found in many food products. In this case, there is an investigation into salmonella infection leading to acute acalculous cholecystitis (AAC). Pancolitis, although mostly caused by ulcerative colitis, …

BACKGROUND AND PURPOSEThe therapeutic potential of different stem cells for ischaemic stroke treatment is intriguing and somewhat controversial. Recent results from our laboratory have demonstrated the potential benefits of human umbilical cord bloo…

A Review of: Johnson, A.M. (2020). Reference and liaison librarians: Endangered species or “vital partners?” Views of academic library administrators. Journal of Library Administration, 60(7), 784-799. https://doi.org/10.1080/01930826.2020.178…

Iron pill gastritis is an underrecognized complication of oral solid iron supplementation, particularly in elderly patients. We present the case of an 83-year-old male with a history of hypertension, hyperlipidemia, type II diabetes, and chronic gas…

Prompt engineering, an emergent discipline at the intersection of Generative Artificial Intelligence (GAI), library science, and user experience design, presents an opportunity to enhance the quality and precision of information retrieval. An innova…

Objective. To develop and evaluate the effectiveness of a structured model for reflective journal writing (RJW) and a grading rubric as part of a student portfolio designed to help Doctor of Pharmacy (PharmD) students create actionable goals. Method…

Major depressive disorder (MDD) is considered a psychiatric disorder and have a relationship with stressful events. Although the common therapeutic approaches against MDD are diverse, a large number of patients do not present an adequate response to…

Age-related neurodegenerative diseases and vascular dementia are major challenges to the modern health care system. Most neurodegenerative diseases are associated with impaired spatial working memory and anxiety-like behavior. Thus, it is important …

Tools to briefly assess diet among US Spanish-speaking adults are needed to identify individuals at risk for cardiometabolic disease (CMD) related to diet. Two registered dietitian nutritionists (RDNs) recruited bilingual medical students to transla…

BACKGROUNDPatella resurfacing in total knee arthroplasty (TKA) involves surgical manipulation of the extensor mechanism, which can weaken or devascularize the patellar bone, quadriceps, and patellar tendon. Patella resurfacing may, in theory, increa…