CHSU Discovery

Progress and perspectives of carbon nanomaterials based electrochemical modifiers for the detection of environmental contaminants

Article

To safeguard human health, environmental pollutants must be thoroughly screened to determine their acceptable limit. Several methods have been developed to identify environmental contaminants. Nevertheless, these methods have several disadvantages. …

Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin

Article

Lysine-proline-valine (KPV) is a C-terminal peptide fragment of α-melanocyte stimulating hormone with potent anti-inflammatory properties. Present study investigates various transdermal enhancement strategies such as iontophoresis (ITP), microneedle…

Tracheomalacia in Adults: An Uncommon Cause of Dyspnea

Article

Tracheomalacia (TM), the most common congenital tracheal defect, is due to compromised cartilage integrity, manifesting in the narrowing of expiratory airways and various respiratory symptoms. While TM is common in infants and toddlers, it is rarely…

The identification and genetic characteristics of Quang Binh virus from field-captured Culex tritaeniorhynchus (Diptera: Culicidae) from Guizhou Province, China

Article

BACKGROUNDMosquitoes carry a variety of viruses that can cause disease in humans, animals and livestock. Surveys for viruses carried by wild mosquitoes can significantly contribute to surveillance efforts and early detection systems. In addition to …

P2Y purinergic signaling in prostate cancer: Emerging insights into pathophysiology and therapy.

Article

Despite recent advances in the treatment landscape for prostate cancer, many challenges still remain. A more profound understanding of prostate cancer pathogenesis and the underlying mechanisms is critical to developing novel therapeutics strategies…

AMPK Signaling Pathway as a Potential Therapeutic Target for Parkinson's Disease

Article

Parkinson's disease (PD) is the second most common neurodegenerative disease caused by the loss of dopaminergic neurons. Genetic factors, inflammatory responses, oxidative stress, metabolic disorders, cytotoxic factors, and mitochondrial dysfunction…

Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2', 4'-Tetrahydroxychalcone

Article

BACKGROUNDLicorice is an herb extensively used for both culinary and medicinal purposes. Various constituents of licorice have been shown to exhibit anti-tumorigenic effect in diverse cancer types. However, majority of these studies focus on the asp…

Airway Management in Patients With Vocal Cord Paralysis: A Review of Intubation Techniques, Intraoperative Challenges, and Outcomes.

Article

Vocal cord paralysis (VCP) presents with unique challenges when managing airways, particularly during endotracheal intubation. This literature review explores the effects of unilateral and bilateral VCP on intubation technique, first-pass success, e…

Orbital Osteomyelitis and Periorbital Abscess Due to Coccidioidomycosis Following Trauma

Article

Ocular involvement due to Coccidioides sp.is extremely rare, and most patients with disseminated coccidioidomycosis present as extrapulmonary or disseminated disease that involves the skin, bone joints, and central nervous system. Here, we describe …

Predictors of Major Bleeding Among Working-Age Adults with Atrial Fibrillation: Evaluating the Effects of Potential Drug-drug Interactions and Switching from Warfarin to Non-vitamin K Oral Anticoagulants

Article

PURPOSEThis study aims to evaluate the associations between switching from warfarin to non-vitamin K oral anticoagulants (NOACs), exposure to potential drug-drug interactions (DDIs), and major bleeding events in working-age adults with atrial fibril…

ABSTRACTAcute kidney injury (AKI) is commonly caused by medications including, but not limited to,aminoglycosides, cephalosporins, penicillins, trimethoprim-sulfamethoxazole, and amphotericin.Among pediatric patients, clindamycin has been widely use…

Utility of nicardipine in the management of hypertensive crises in adults with reduced ejection fractions

Article

BACKGROUNDNicardipine is commonly used in the management of hypertensive crises, except those involving cardiac contractility defects despite its ability to reduce afterload and pulmonary congestion. Consequently, there is limited literature evaluat…

Structured Interviews Reveal That Reference and Liaison Librarians—as Engaged, Proactive Partners—are Vital to the Academic Enterprise

Review Article

A Review of: Johnson, A.M. (2020). Reference and liaison librarians: Endangered species or “vital partners?” Views of academic library administrators. Journal of Library Administration, 60(7), 784-799. https://doi.org/10.1080/01930826.2020.178…

When Fantasy Feels Too Real: The Psychological Toll of Deep Media Attachment.

Article

Parasocial relationships (PSRs) are emotional relationships developed with a media figure. These relationships may take the form of friendship, romantic attachments, or the embodiment of the persona. This case study highlights the psychological impa…

Integrating PICO principles into generative artificial intelligence prompt engineering to enhance information retrieval for medical librarians

Article

Prompt engineering, an emergent discipline at the intersection of Generative Artificial Intelligence (GAI), library science, and user experience design, presents an opportunity to enhance the quality and precision of information retrieval. An innova…

The Irony of Iron Pill Gastritis: A Case of Delayed Recognition and Persistent Injury in an Elderly Patient

Article

Iron pill gastritis is an underrecognized complication of oral solid iron supplementation, particularly in elderly patients. We present the case of an 83-year-old male with a history of hypertension, hyperlipidemia, type II diabetes, and chronic gas…

Non-pharmacological therapeutic paradigms in stress-induced depression: from novel therapeutic perspective with focus on cell-based strategies

Article

Major depressive disorder (MDD) is considered a psychiatric disorder and have a relationship with stressful events. Although the common therapeutic approaches against MDD are diverse, a large number of patients do not present an adequate response to…

Curcumin Ameliorates the Cd-Induced Anxiety-like Behavior in Mice by Regulating Oxidative Stress and Neuro-Inflammatory Proteins in the Prefrontal Cortex Region of the Brain.

Article

Age-related neurodegenerative diseases and vascular dementia are major challenges to the modern health care system. Most neurodegenerative diseases are associated with impaired spatial working memory and anxiety-like behavior. Thus, it is important …

A Comprehensive Reflective Journal-Writing Framework for Pharmacy Students to Increase Self-Awareness and Develop Actionable Goals

Article

Objective. To develop and evaluate the effectiveness of a structured model for reflective journal writing (RJW) and a grading rubric as part of a student portfolio designed to help Doctor of Pharmacy (PharmD) students create actionable goals. Method…

Incorporating Augmented Reality Into Anatomy Education in a Contemporary Medical School Curriculum

Article

Anatomy education in the medical school curriculum has encountered considerable challenges during the last decade. The exponential growth of medical science has necessitated a review of the classical ways to teach anatomy to shorten the time student…