CHSU Discovery

Top 100 cited articles in osteopathic medical education: A bibliometric analysis

Article

Context Bibliometric analysis is a method for analyzing the existing literature of a specific research area. Because it provides information about current research trends, the analysis can highlight attributes of frequently cited articles and ident…

Diffuse Bi-hemispheric Cortical Infarction Secondary to Cerebral Air Embolism After Elective Esophagogastroduodenoscopy: A Case Report and Review of Literature

Article

Cerebral air embolism (CAE) is a rare entity and is more often secondary to iatrogenic causes. We present a rare case of CAE post esophagogastroduodenoscopy (EGD) with a shower of emboli resulting in diffuse cortical infarction. An 80-year-old man w…

Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness

Article

In our practice, we have noticed an increased number of patients requiring mesh removal due to a systemic reaction to their implant. We present our experience in diagnosing and treating a subpopulation of patients who require mesh removal due to a p…

Renin angiotensin aldosterone system in pulmonary fibrosis: Pathogenesis to therapeutic possibilities.

Review Article

Pulmonary fibrosis is a devastating lung disease with multifactorial etiology characterized by alveolar injury, fibroblast proliferation and excessive deposition of extracellular matrix proteins, which progressively results in respiratory failure an…

Progress and perspectives of carbon nanomaterials based electrochemical modifiers for the detection of environmental contaminants

Article

To safeguard human health, environmental pollutants must be thoroughly screened to determine their acceptable limit. Several methods have been developed to identify environmental contaminants. Nevertheless, these methods have several disadvantages. …

Single Accreditation and The Match: How Does the Change Affect Osteopathic Graduates?

Article

This article was migrated. The article was marked as recommended. There is a predicted serious shortage of physicians in the US. To overcome this problem, medical schools have expanded at the behest of the US Government by number and by overall grad…

Wnt Pathway-Targeted Therapy in Gastrointestinal Cancers: Integrating Benchside Insights with Bedside Applications

Article

The Wnt signaling pathway is critical in the onset and progression of gastrointestinal (GI) cancers. Anomalies in this pathway, often stemming from mutations in critical components such as adenomatous polyposis coli (APC) or β-catenin, lead to uncon…

Optimal Glucose Reduction in Diabetic Emergencies (OG-RIDE).

Article

BACKGROUNDTo minimize the risk of cerebral edema in the management of hyperglycemic emergencies, guidelines recommend gradually decreasing serum glucose levels, but there is limited literature validating these reduction goals or evaluating outcomes …

Tracheomalacia in Adults: An Uncommon Cause of Dyspnea

Article

Tracheomalacia (TM), the most common congenital tracheal defect, is due to compromised cartilage integrity, manifesting in the narrowing of expiratory airways and various respiratory symptoms. While TM is common in infants and toddlers, it is rarely…

Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin

Article

Lysine-proline-valine (KPV) is a C-terminal peptide fragment of α-melanocyte stimulating hormone with potent anti-inflammatory properties. Present study investigates various transdermal enhancement strategies such as iontophoresis (ITP), microneedle…

National Survey Exploring Drug Screening in Pharmacy Programs

Article

Objective. To explore drug screening programs, including requirements, policies, and procedures among pharmacy programs; frequency of drug-related incidents; and types of substances misused by pharmacy students. Methods. IRB-approved web-based and p…

A Comprehensive Review of Novel FDA-Approved Psychiatric Medications (2018-2022)

Article

Mental health disorders are among the top leading causes of disease burden worldwide and many patients have high levels of treatment resistance. Even though medications offer improvement to some patients, antidepressants are only effective in about …

Training Medical Students in Diet Assessment and Brief Counseling.

Article

Poor dietary choices are a leading cause of chronic disease, but nutrition is rarely discussed in clinical practice. Nutrition is taught in less than a third of medical schools and physicians in practice empirically report low levels of comfort and …

A Worsening Cough: An Unusual Presentation of Malignant Mesothelioma

Article

Localized malignant pleural mesothelioma (LMPM) is a rare cancer with poor survival rates. Often affecting males with asbestos exposure, we report a case of a 56-year-old female with no history of occupational exposure presenting with a worsening co…

Mesenchymal stem cell-derived exosomes improve neurogenesis and cognitive function of mice with methamphetamine addiction: A novel treatment approach

Article

BACKGROUNDMethamphetamine (METH) is a psychostimulant substance with highly addictive and neurotoxic effects, but no ideal treatment option exists to improve METH-induced neurocognitive deficits. Recently, mesenchymal stem cells (MSCs)-derived exoso…

Mitotherapy restores hippocampal mitochondrial function and cognitive impairment in aged male rats subjected to chronic mild stress

Article

This study aimed to determine the effects of mitotherapy on learning and memory and hippocampal kynurenine (Kyn) pathway, mitochondria function, and dendritic arborization and spines density in aged rats subjected to chronic mild stress. Twenty-eigh…

Scheuermann Kyphosis: Current Concepts and Management

Article

PURPOSE OF REVIEWScheuermann's kyphosis (SK) is a developmental deformity of the spine that affects up to 8% of children in the US. Although, the natural progression of SK is noted to be gradual over years, severe deformity can be associated with si…