CHSU Discovery

A Retrospective Study of Outcomes in a Rural Pediatric Population Treated for Venous Insufficiency

Article

BACKGROUNDEndovascular radiofrequency ablation (RFA) and Endovascular Laser Ablation (EVLA) are minimally invasive methods to safely treat symptomatic varicose veins in pediatric patients. This research aimed to review the management of pediatric pa…

Breathing life into learning about air quality: developing and implementing environmental health outreach with high school students

Article

Background: The San Joaquin Valley (SJV) is comprised of diverse populations that cumulatively are medically underserved and experience significant air pollution. The SVJ regularly has poor air quality and does not meet the state and federal a…

Stem cell treatment improves post stroke neurological outcomes: a comparative study in male and female rats.

Article

BACKGROUND AND PURPOSEThe therapeutic potential of different stem cells for ischaemic stroke treatment is intriguing and somewhat controversial. Recent results from our laboratory have demonstrated the potential benefits of human umbilical cord bloo…

Acute Acalculous Cholecystitis in a Patient With Pancolitis: A Case Report

Article

Salmonella is an infectious bacterial organism found in many food products. In this case, there is an investigation into salmonella infection leading to acute acalculous cholecystitis (AAC). Pancolitis, although mostly caused by ulcerative colitis, …

Comparison of endoscopic thyroidectomy by complete areola approach and conventional open surgery in the treatment of differentiated thyroid carcinoma: A retrospective study and meta-analysis

Article

BackgroundThe feasibility of endoscopic thyroidectomy by complete areola approach (ETCA) remains controversial. This study was conducted by combining our clinical data with the data obtained from a systematic review literature search to examine the …

Parental refusal of childhood vaccines is a growing public health concern. Numerous reasons exist for this refusal, including religious, personal, and philosophical beliefs, and safety concerns. However, parental refusal of childhood vaccines …

Epithelial-to-Pericyte Transition in Cancer

Article

During epithelial-to-mesenchymal transition (EMT), cells lose epithelial characteristics and acquire mesenchymal properties. These two processes are genetically separable and governed by distinct transcriptional programs, rendering the EMT outputs h…

Acute Large Bowel Obstruction Post Umbilical Hernia Repair Surgery: A Case Report

Article

While large bowel obstruction (LBO) is a less common cause of bowel obstruction, it has a broad range of differentials. Its most common etiology in the United States is colorectal adenocarcinoma. Patients usually present with diffuse abdominal pain,…

Comparison of rerupture rates after operative and nonoperative management of Achilles tendon rupture in older populations: Systematic review and meta-analysis

Article

BackgroundThis systematic review and meta-analysis investigated the treatment for Achilles tendon rupture (ATR) associated with the lowest risk of rerupture in older patients.MethodsFive databases were searched through September 2022 for studies pub…

ABSTRACTAcute kidney injury (AKI) is commonly caused by medications including, but not limited to,aminoglycosides, cephalosporins, penicillins, trimethoprim-sulfamethoxazole, and amphotericin.Among pediatric patients, clindamycin has been widely use…

Incorporating Augmented Reality Into Anatomy Education in a Contemporary Medical School Curriculum

Article

Anatomy education in the medical school curriculum has encountered considerable challenges during the last decade. The exponential growth of medical science has necessitated a review of the classical ways to teach anatomy to shorten the time student…

Incorporating ACPE Standards in a Holistic Approach to School Operations and Accreditation

Article

Auburn University Harrison School of Pharmacy (AUHSOP) implemented a comprehensive, holistic process of continuous quality improvement (CQI) for its program using the Accreditation Council for Pharmacy Education's (ACPE) Accreditation Standards as t…

Exosomes as a therapeutic tool to promote neurorestoration and cognitive function in neurological conditions: Achieve two ends with a single effort

Article

Exosomes possess a significant role in intercellular communications. In the nervous system, various neural cells release exosomes that not only own a role in intercellular communications but also eliminate the waste of cells, maintain the myelin she…

The Impact of COVID-19 on Outcomes of Ischemic Colitis: A Nationwide Retrospective Analysis

Article

BackgroundIschemic colitis is the most common presentation of mesenteric ischemia and is associated with significant morbidity and mortality. Coagulopathy has been associated with the development of ischemic colitis. Coronavirus disease 2019 (COVID-…

Acute Interpositional Fat Autograft Does Not Protect Against Bar Formation in Physeal Fractures

Article

BACKGROUNDLong-bone fractures in children can lead to premature physeal bar formation and growth disturbance. Bar excision has been studied, but data on prophylactic tissue interposition into physeal fractures are limited. This study used an establi…

High-fat diet-induced glucose dysregulation is independent of changes in islet ACE2 in mice

Article

While restoration of ACE2 activity in the pancreas leads to improvement of glycemia in experimental models of Type 2 diabetes, global deficiency in ACE2 disrupts β-cell function and impairs glucose tolerance in mice, demonstrating the physiological …