CHSU Discovery

Abstract Hepatocellular carcinoma (HCC) is the third largest cause of cancer-induced mortality worldwide. The MYConcogene is a prevalent driver of human neoplasia, including HCC. Immune checkpoint inhibitors have succeeded in treating many MYC-drive…

Abstract Globally, obesity is defined by the Body Mass Index (BMI) greater than or equal to 30 kg/m2. BMI is calculated by dividing weight in kilograms over height in meters. Just under the category of obesity, is overweight, which is defined as BM…

Background Addressing the gap in connecting unhoused and housing-insecure individuals with communityresources is crucial, as these resources are often underutilized due to a lack of awareness. Acentralized resource directory can bridge this gap, as …

Abstract Type 2 Diabetes (T2D) is a prevalent chronic condition affecting diverse populations across the Central Valley, an area known for its rich cultural diversity. Effective diabetes education is crucial for managing the disease, yet standa…

Abstract Colorectal cancer (CRC) is a significant public health concern, with screening playing a vital role in reducing morbidity and mortality. However, disparities in screening persist, particularly in underserved regions such as the Centra…

Abstract Food insecurity is a social determinant of health comprised of a hierarchy of four domains: availability, access, utilization, and stability. Reliable access to food is particularly limited in rural areas like south-central Pennsylvania and…

Abstract:A 2020 study conducted in the United Kingdom of 76 general practices, including 622 patients, examined the efficacy of combining self-monitoring blood pressure with guided self-management. Digital intervention provided feedback of blood pre…

Abstract: Caffeine is a widely consumed stimulant present in coffee, tea, chocolate, and energy drinks. Not only does caffeine improve mood and relief from headaches, but also it is linked to reduction of risk strokes, Parkinson's, and Alzheime…

Abstract • Osteopathic medicine (OMM) is a hands-on, holistic approach focusedon the body's self-healing abilities and the relationship betweenstructure and function.• DOs are fully licensed physicians trained in both standard medical care…

Amongst 40% of population with SLE who test positive for Antiphospholipid antibodies (aPL) only 7-15% of the patients develop Antiphospholipid antibody syndrome. Repeat aPL after a duration of 12 or more weeks and lack of continuity of care can some…

Abstract:Introduction and Background: Hemophagocytic lymphohistiocytosis (HLH) is a severe, life-threatening inflammatory disorder, with an estimated annual incidence of 1.5 per million, affecting multiple organ systems and carrying a high risk of m…

Primary brain tumors are considered relatively rare. Most cases of brain tumors consist of metastatic disease from the lung, breast, colon, and kidney. The most common primary brain tumors include meningiomas, glioblastomas, and astrocytomas. Brain …

Abstract:  Purpose of Study: The patient, a previously healthy 32-year-old female, initially presented with psychiatric symptoms, including psychosis, agitation, and delusions. Subsequent neurological examination revealed the presence of s…

Abstract Non-melanoma skin cancers (NMSCs), which include basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are among the most prevalent malignancies worldwide and continue to rise in incidence due to factors such as prolonged…

Abstract Context: Premedical preparatory programs at osteopathic medical schools that recruit students from medically underserved areas (MUAs) may promote interest in practicing osteopathic medicine in underserved areas. In these programs, fostering…

Abstract Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally. Incidence rates among individuals under 50 years are rising, which has led to the lowering of the recommended screening age from 50 to 45 years for those at an av…

Abstract Incretins are hormones that regulate insulin release from the pancreas and encourage a decrease in blood glucose levels. The primary incretins are Glucagon like peptide 1 – receptor agonists (GLP-1 RAs) and gastric inhibitory polypept…

Background:COVID-19, also known as SARS-CoV-2, is a novel coronavirus that has had a profound impact on the healthcare field. While it is primarily a respiratory infection that commonly presents with symptoms such as dry cough, shortness of breath, …

Pneumocystis pneumonia (PCP) is caused by Pneumocystis Jirovecii. HIV is an RNA retrovirus that infects CD4 (T-helper) cells, which drop from normal level of 600-1000 cells/mm3 at rate of 50-100 per year in untreated people. CDC defines HIV+ person …

Abstract The COVID-19 pandemic highlighted a growing mental health crisis in pediatric populations, especially regarding treatment-resistant depression (TRD), mood disorders, and Post-Traumatic Stress Disorder (PTSD).​ Ketamine, originally developed…