CHSU Discovery

Abstract Prostate cancer is both the most frequently diagnosed malignancy among men worldwide and the most significant contributor to cancer-associated mortalities in the United States. Commonly known risk factors include family history,  …

Abstract This study assessed the impact of treating Obstructive Sleep Apnea (OSA) with positive airway pressure (PAP) on the risk of postoperative complications. It used data on PAP adherence collected from a large, integrated healthcare system data…

Abstract Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally. Incidence rates among individuals under 50 years are rising, which has led to the lowering of the recommended screening age from 50 to 45 years for those at an av…

Abstract:Introduction and Background: Hemophagocytic lymphohistiocytosis (HLH) is a severe, life-threatening inflammatory disorder, with an estimated annual incidence of 1.5 per million, affecting multiple organ systems and carrying a high risk of m…

Primary brain tumors are considered relatively rare. Most cases of brain tumors consist of metastatic disease from the lung, breast, colon, and kidney. The most common primary brain tumors include meningiomas, glioblastomas, and astrocytomas. Brain …

Abstract Context: Premedical preparatory programs at osteopathic medical schools that recruit students from medically underserved areas (MUAs) may promote interest in practicing osteopathic medicine in underserved areas. In these programs, fostering…

Abstract:  Purpose of Study: The patient, a previously healthy 32-year-old female, initially presented with psychiatric symptoms, including psychosis, agitation, and delusions. Subsequent neurological examination revealed the presence of s…

Abstract Osteopathic Values in Fostering a Sustainable Work Environment: Osteopathic values help create a sustainable and supportive environment for pediatric surgeons. These principles encourage collaborative care models that address the surgeon's …

Background CRPS is a chronic pain syndrome often triggered by trauma or nerveinjury1.• Type 2 CRPS involves confirmed nerve damage.• Symptoms include burning pain, swelling, skin changes, and allodynia.• CRPS can affect the GI, autono…

Abstract Throughout history, postmortem dissections, primarily involving cadavers,have been a cornerstone of anatomical education. However, as medicalcurricula evolve, there has been a shift away from traditional cadavericdissections. To address thi…

Background: 20% of older adults experiencing mental and neurological disorders.During the height of the COVID-19 pandemic and the shelter-in-place orders, loneliness and social isolation were higher than ever before.Depression is commonly underdiagn…

Total hip arthroplasty (THA) involves the replacement of pathologic hip joints withprosthetic implants to restore functionality and alleviate pain. Current implants forreplacing the acetabulum use a "press-fit" application with no screws; however, i…

Abstract Hepatocellular carcinoma (HCC) is the third largest cause of cancer-induced mortality worldwide. The MYConcogene is a prevalent driver of human neoplasia, including HCC. Immune checkpoint inhibitors have succeeded in treating many MYC-drive…

Abstract Total hip arthroplasty (THA) is a surgical procedure that replacesdamaged hip joints with artificial implants, effectively treatingconditions like osteoarthritis, rheumatoid arthritis, and avascularnecrosis. Despite its success, challenges …

Abstract:Immunization completion in the United States has been a topic discussed for decades, in part due to parents being misinformed or lacking knowledge regarding the basis of immunizations. Furthermore, due to the recent COVID-19 pandemic, there…

Background: The imperative role of dietary interventions in managing chronic diseases is well-established, yet medical school graduates often feel ill-equipped to provide nutritional guidance to patients. In response, California Health Sciences Univ…

Abstract Community Health Worker (CHW) Programs are the training and implementation of community health workers (CHWs) into the community to lessen health disparities and increase healthcare access in underserved populations. CHWs share the language…

Abstract:Introduction: Autoimmune hepatitis is a rare autoimmune liver disease characterized by elevated liver enzymes, hypergammaglobulinemia, and autoantibodies. It predominantly affects young to middle-aged women, but can also occur in the elderl…

Abstract:Intravascular lithotripsy (IVL) is a novel technique for the treatment of severely calcified plaque lesions that uses acoustic shockwaves in a balloon-based delivery system. Shockwaves induce calcium fractures, which facilitate stent expans…

Abstract   Cancer remains a significant global health burden, with treatment primarily focused on biomedical approaches. Lifestyle factors, particularly nutrition, are often overlooked in standard cancer care. Growing evidence suggests that nu…