CHSU Discovery

Abstract Non-melanoma skin cancers (NMSCs), which include basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are among the most prevalent malignancies worldwide and continue to rise in incidence due to factors such as prolonged…

Abstract:Introduction and Background: Hemophagocytic lymphohistiocytosis (HLH) is a severe, life-threatening inflammatory disorder, with an estimated annual incidence of 1.5 per million, affecting multiple organ systems and carrying a high risk of m…

Abstract:  Purpose of Study: The patient, a previously healthy 32-year-old female, initially presented with psychiatric symptoms, including psychosis, agitation, and delusions. Subsequent neurological examination revealed the presence of s…

Background: With the prevalence of obesity, hypertension, and the convenience of unhealthy eating choices, Type II Diabetes is a growing disease that has affected millions of Americans, both young and old. Nutrition is a major component in improving…

Abstract The COVID-19 pandemic highlighted a growing mental health crisis in pediatric populations, especially regarding treatment-resistant depression (TRD), mood disorders, and Post-Traumatic Stress Disorder (PTSD).​ Ketamine, originally developed…

Abstract:NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are impl…

Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone primarily secreted by L-cells in the gut after eating, prompting insulin release to reduce blood sugar Levels. In pancreatic β-cells, GLP-1 binds to its receptor, activating adenyl…