CHSU Discovery

Abstract MicroRNAs (miRNAs) are key regulators of post-transcriptional gene expression in the nervous system, where they fine-tune gene activity. Highly enriched in neural tissue, miRNAs influence neuroplasticity by modulating processes such as neur…

  NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are imp…

Abstract:NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are impl…

Abstract Myelodysplastic syndrome (MDS) has been seen in U2AF1 mutations in patients younger than 50 with high risk of developing Acute Myeloid Leukemia. It is a rare complication associated with dyskeratosis congenita along with features of avascul…

Abstract • Osteopathic medicine (OMM) is a hands-on, holistic approach focusedon the body's self-healing abilities and the relationship betweenstructure and function.• DOs are fully licensed physicians trained in both standard medical care…

Abstract Type 2 Diabetes (T2D) is a prevalent chronic condition affecting diverse populations across the Central Valley, an area known for its rich cultural diversity. Effective diabetes education is crucial for managing the disease, yet standa…

Abstract Colorectal cancer (CRC) is a significant public health concern, with screening playing a vital role in reducing morbidity and mortality. However, disparities in screening persist, particularly in underserved regions such as the Centra…

Abstract:A 2020 study conducted in the United Kingdom of 76 general practices, including 622 patients, examined the efficacy of combining self-monitoring blood pressure with guided self-management. Digital intervention provided feedback of blood pre…

Abstract Food insecurity is a social determinant of health comprised of a hierarchy of four domains: availability, access, utilization, and stability. Reliable access to food is particularly limited in rural areas like south-central Pennsylvania and…

Abstract: Caffeine is a widely consumed stimulant present in coffee, tea, chocolate, and energy drinks. Not only does caffeine improve mood and relief from headaches, but also it is linked to reduction of risk strokes, Parkinson's, and Alzheime…

Abstract Introduction  Food insecurity is limited access to nutritious and safe foods. As a response to food insecurity in Merced, Golden Valley Health Center (GVHC) has created their Food Pharmacy to address food insecurity and provide clie…

Abstract Background: There is a growing body of evidence outlining the symptomatic evolution and long-term healthcomplications following Sars-CoV-2 infection. There is a greater risk of developing persistent symptoms following recovery from COVID-19…

Abstract    

Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone primarily secreted by L-cells in the gut after eating, prompting insulin release to reduce blood sugar Levels. In pancreatic β-cells, GLP-1 binds to its receptor, activating adenyl…

Abstract Obesity is most commonly defined by the Body Mass Index (BMI) greater than or equal to 30 kg/m2. BMI is calculated by dividing weight in kilograms over height in meters. Just under the category of obesity, is overweight, which is defined a…

Abstract Ischemic stroke leads to motor, sensory, and cognitive impairments that reduce quality of life.​ Neuroplasticity enables the brain to reorganize and form new connections essential for recovery.​ Rehabilitation leverages neuroplasticity, wit…

Abstract   Cancer remains a significant global health burden, with treatment primarily focused on biomedical approaches. Lifestyle factors, particularly nutrition, are often overlooked in standard cancer care. Growing evidence suggests that nu…

Abstract:Intravascular lithotripsy (IVL) is a novel technique for the treatment of severely calcified plaque lesions that uses acoustic shockwaves in a balloon-based delivery system. Shockwaves induce calcium fractures, which facilitate stent expans…

Abstract:Introduction: Autoimmune hepatitis is a rare autoimmune liver disease characterized by elevated liver enzymes, hypergammaglobulinemia, and autoantibodies. It predominantly affects young to middle-aged women, but can also occur in the elderl…

Abstract:Introduction and Background: Limited data exist on the epidemiology and prevalenceof various etiologies of pediatric esophageal dysphagia (PED).Esophagogastroduodenoscopy (EGD) is commonly used as the standard diagnosticprocedure in pediatr…