CHSU Discovery

  NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are imp…

• Hyperkalemia (K+ > 5.5 mmol/L) is a serious electrolyte abnormality which may cause life-threatening cardiac arrhythmias.• Pharmacological management of hyperkalemia includes the administration of agents to (1) stabilize car…

Abstract In this ongoing cross-sectional study, a survey was created to record the symptoms of patients with fibromyalgia (FM) severity, including chronic pain, chronic fatigue, and sleep disturbances, on a scale from 0 (no symptom) to 10 (worst int…

Abstract  Introduction: The treatment for pulmonary tuberculosis (TB) is 4 months of rifampin, isoniazid, pyrazinamide, and ethambutol (RIPE) followed by 2 months of rifampin and isoniazid only (RI). Anti-TB drugs and TB can both cause encephal…

Abstract Psychiatric conditions often have variable presentations, especially as many of these disorders have similar symptoms and significant comorbidity. Multiple psychiatric disorders occurring concurrently are often mistaken as a single disease …

Abstract: Background: Anterior Cruciate Ligament (ACL) reconstruction is one of the most common surgical procedures in the field of orthopedic surgery; this is especially true in younger athletes. Injury to the ACL commonly occurs during load-bearin…

Parental refusal of childhood vaccines is a growing public health concern. Numerous reasons exist for this refusal, including religious, personal, and philosophical beliefs, and safety concerns. However, parental refusal of childhood vaccines is not…

Abstract: Introduction and Background: In 2011, there were over 65,000 cases and over 9,000 deaths from melanoma in the United States, alone. Targeted therapy and immunotherapy were landmark steps in melanoma treatment but combined immunotherapy has…

Guillain-Barre syndrome (GBS) has been recognized as a rare complication following infection with SARS-CoV-2 (COVID-19). We report a case of GBS in a 69-year-old male with negative saliva test, but positive COVID serology. Considering that there wer…

Purpose of the Study: Complex regional pain syndrome (CRPS) is a severely disabling chronic pain condition that typically manifests in the upper or lower extremities following an injury, surgery, or stroke. CRPS is poorly understood, accordingly, th…

Abstract Age-related macular degeneration (AMD) is the fourth leading cause of blindness in older adults and is estimated to affect 8.7% of the global population. The neovascular, or exudative (“wet”), form of the disease&…

Abstract This case study focuses on a woman in her late fifties with past medical history of recurrent childhood respiratory and skin infections presenting to the pulmonology clinic with dyspnea and wheezing only partially relieved with inhalers and…

Intro:The Solute Carrier 22 (SLC22) family is perhaps best known as a family of “drug” transporters.OCT1, OAT1, and OAT3 are among the most important multi-specific drug transporters in thebody. The SLC22 family of transporters can be se…

Abstract Shingles is the reactivation of the chicken pox virus in the body leading to a painful rash along a nerve pathway. Shingles can lead to postherpetic neuralgia (PHN) which is a complication due to shingles. It occurs if your nerve fibers are…

Abstract Seeking help for mental health concerns is a social barrier that is just part of the battle for the Hispanic/Latino/a/x community– financial and systemicdisadvantages have created a significant gap in the accessibility and quality of …

This study will aim to identify the Latino/a/e/x communities’ perspectives regarding the term Latinx. The term originated in the early 2000s and began gaining popularity with the media around 2010 (Guidotti-Hernández, 2017). The term la…

Hypertriglyceridemia (HTG): triglyceride levels ≥ 150 mg/dL • HTG is associated with an increased risk of atherosclerotic cardiovascular disease and pancreatitis • ~20% acute pancreatitis cases result from severe HTG ( > 500 mg/dL) &…

Abstract Severe hyponatremia (serum sodium level ≤ 120 mmol/L) management guidelines recommend administering hypertonic sodium chloride (HTS) to initially raise serum sodium levels by 4-6 mmol/L. ​ While various HTS doses and concentrati…

Abstract Colorectal cancer (CRC) is a significant public health concern, with screening playing a vital role in reducing morbidity and mortality. However, disparities in screening persist, particularly in underserved regions such as the Centra…

Abstract Type 2 Diabetes (T2D) is a prevalent chronic condition affecting diverse populations across the Central Valley, an area known for its rich cultural diversity. Effective diabetes education is crucial for managing the disease, yet standa…