CHSU Discovery

Parental refusal of childhood vaccines is a growing public health concern. Numerous reasons exist for this refusal, including religious, personal, and philosophical beliefs, and safety concerns. However, parental refusal of childhood vaccines is not…

Abstract: Introduction and Background: In 2011, there were over 65,000 cases and over 9,000 deaths from melanoma in the United States, alone. Targeted therapy and immunotherapy were landmark steps in melanoma treatment but combined immunotherapy has…

Guillain-Barre syndrome (GBS) has been recognized as a rare complication following infection with SARS-CoV-2 (COVID-19). We report a case of GBS in a 69-year-old male with negative saliva test, but positive COVID serology. Considering that there wer…

Purpose of the Study: Complex regional pain syndrome (CRPS) is a severely disabling chronic pain condition that typically manifests in the upper or lower extremities following an injury, surgery, or stroke. CRPS is poorly understood, accordingly, th…

Abstract Alien Hand Syndrome (AHS) is a rare neurological disorder caused by lesions in thefrontal lobe, corpus callosum, or parietal lobe, leading to a disconnect between motorcontrol, sensory input, and body awareness (1).• The pathophysiolog…

Abstract   Acknowledgments: We would like to extend our gratitude to Dr. Wang and his clinic for their contribution to this study, with special thanks to Yichun Tao for help with data collection. We would also like to express our gratitude tow…

Abstract The Central Valley of California has a rate of diabetes that is higher than the national average. Patients who have been diagnosed with diabetes must maintain blood sugar levels within a set range to avoid complications. There are a variety…

AbstractIntroduction: Spinal anesthesia (SA) allows total joint arthroplasty (TJA) to be performed while minimizing opioids and systemic anesthetic agents compared to general anesthesia (GA). SA has been associated with shortened postoperative recov…

Abstract Myelodysplastic syndrome (MDS) has been seen in U2AF1 mutations in patients younger than 50 with high risk of developing Acute Myeloid Leukemia. It is a rare complication associated with dyskeratosis congenita along with features of avascul…

Abstract:NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are impl…

  NADPH oxidases (NOXs) are newly identified enzymes that generate intracellular reactive oxygen species (ROS) in skin cells. Recent studies demonstrated that NOX1 holoenzyme is expressed in human keratinocytes and melanocytes, which are imp…

Background: Facts: While hypertension is one of the highest prevalent diseases in the United States; control of blood pressure to an acceptable range is a shocking 45%.1 As of 2020, local data from Fresno Community Health Improvement Partnership (F…

Neuromyelitis Optica Spectrum Disorders (NMOSD) aka’s Devic Disease or Neuromyelitis Optica (NMO) is a rare disease. It has 10x high predilection to female than male, ages 32-41, primarily African American and Afro-Caribbean with diagnosing cr…

Introduction: Type 2 diabetes is a chronic disease that is related to insulin resistance and dysregulation of energy metabolism.The relationship of diabetes and hyperglycemia to atrophy in specific areas of the brain have not been fully investigated…

Abstract   Cancer remains a significant global health burden, with treatment primarily focused on biomedical approaches. Lifestyle factors, particularly nutrition, are often overlooked in standard cancer care. Growing evidence suggests that nu…

Abstract Obesity is most commonly defined by the Body Mass Index (BMI) greater than or equal to 30 kg/m2. BMI is calculated by dividing weight in kilograms over height in meters. Just under the category of obesity, is overweight, which is defined a…

Abstract Ischemic stroke leads to motor, sensory, and cognitive impairments that reduce quality of life.​ Neuroplasticity enables the brain to reorganize and form new connections essential for recovery.​ Rehabilitation leverages neuroplasticity, wit…

Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone primarily secreted by L-cells in the gut after eating, prompting insulin release to reduce blood sugar Levels. In pancreatic β-cells, GLP-1 binds to its receptor, activating adenyl…

Abstract:A literature review was performed which found that many patients with cervixes face financial, cultural, and language barriers when accessing cervical cancer screenings1. The most significant concerns reported by patients regarding access t…

Hypertension is the leading cause of cardiovascular disease, which is an ever-growing issue that continues to plague the United States.