Maximizing Neuroplasticity After Ischemic Stroke by Rehabilitation: Role of Mediators
- Afable J. [1] ,
- Dajani M. [1] ,
- Hill C. [1] ,
- Khoury D. [1] ,
- Magardichian M. [1] ,
- Singh R. [1] and
- Dr. Mohaddes G. [1]
Repository
Description
Abstract
Ischemic stroke leads to motor, sensory, and cognitive impairments that reduce quality of life. Neuroplasticity enables the brain to reorganize and form new connections essential for recovery. Rehabilitation leverages neuroplasticity, with effectiveness influenced by timing, intensity, and individual differences. This study reviewed literature from 2000 to 2024 on stroke rehabilitation and neuroplasticity-related molecular factors. Rehabilitation enhances neuroplasticity through neural circuit remodeling and experience-dependent plasticity. Physical, occupational, and cognitive therapies promote functional recovery by strengthening adaptive brain pathways. Neurotransmitters and exercise-induced molecules support synaptic remodeling and brain function, emphasizing personalized rehabilitation.
Affiliations
- California Health Sciences University College of Osteopathic Medicine