CHSU Discovery

Abstract

• Breast and prostate cancer are among the most commonly
diagnosed cancers worldwide, highlighting the need for effective
therapeutic strategies.
• Despite advances in treatment, many breast and prostate cancer
cell lines develop resistance to conventional therapies, reducing
long-term treatment success.
• Tumor cell viability is a key indicator of treatment response and
is commonly used to evaluate the effectiveness of experimental
therapies.
• Plasma-activated media (PAM) has recently emerged with the
potential to increase both effectiveness and selectivity of
chemotherapeutics.
• PAM is a type of media that has been treated with ionized
atmospheric air, known as cold plasma, a highly energized state
of matter that creates reactive oxygen and nitrogen species
(RONS) responsible for the anti-cancer properties.

Purpose

Evaluation of PAM with and without chemotherapeutic drugs in
reducing the cell viability of normal and malignant breast and
prostate cancer cells.