CHSU Discovery

Effects of Glucagon-Like Peptide-1 Receptor Agonists on Glaucoma and Ocular Hypertension

2026

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Description

Abstract

Glaucoma is a disease of the eyes that can cause optic nerve damage, loss of retinal cells, and an enlargement of the optic cup. This condition is commonly linked to increased intraocular pressure (IOP), leading to angleclosure or open-angle glaucoma. Conventional treatments for glaucoma include miotic agents, beta blockers, alpha-2 agonists, carbonic anhydrase inhibitors, mannitol, prostaglandin analogs, laser trabeculoplasty, cyclophotocoagulation, cyclocryocoagulation, insertion of stents, sclerotomy, and trabeculectomy. The use of glucagon-like peptide-1 receptor agonists (GLP1RAs) in patients with glaucoma was assessed for beneficial or detrimental effects on prognosis.

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Affiliations

  1. California Health Sciences University College of Osteopathic Medicine
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