CHSU Discovery

Abstract

Non-Arteritic Anterior Ischemic Neuropathy (NAION) is currently one of the most common causes of acute optic nerve injury in individuals over 50. This sudden, painless loss of monocular vision is due to an obstructed blood supply to the anterior part of the optic nerve. Although the pathophysiology is still unclear, the onset of NAION is hypothesized to be due to apoptosis of retinal ganglion cells from ischemia of the short posterior ciliary arteries and subsequent constriction of ocular microcirculation. This narrative review aims to synthesize current findings on a potential association between GLP-1RA use and NAION.