CHSU Discovery

Abstract:
This comprehensive literature review addresses the scarcity and limited study of
hypotension treatments compared to abundant antihypertensive drugs. Hypotension,
categorized as absolute, relative, or orthostatic, has diverse causes. This review
explores various treatments, including drugs affecting the sympathetic nervous system,
such as midodrine, dihydroergotamine, and ergotamine, which have shown efficacy in
managing hypotension. Dopamine agonists/antagonists and other drugs such as
ephedrine, norepinephrine, and fludrocortisone are also discussed, each with distinct
mechanisms and applications. Additionally, adjunctive agents such as non-steroidal
anti-inflammatory agents, caffeine, and monoamine oxidase inhibitors are reviewed for
their effects on blood pressure. This review underscores the importance of
understanding the efficacy and safety profiles of hypotension treatments to guide
healthcare professionals in optimal drug selection and management, emphasizing the
need for further research and comparative studies for evidence-based guidelines.