The OCTN-related transporter SLC22A15 regulates carnitine, antioxidants and inflammatory cytokines in vivo
- Zhang P. [1] ,
- Falah K. [3] ,
- Joseph B.C. [4] ,
- Granados J.C. [2] ,
- MacMullen C. [6] ,
- Davis R.L. [6] and
- Nigam S.K. [5]
2024
Repository
Description
Intro:
The Solute Carrier 22 (SLC22) family is perhaps best known as a family of “drug” transporters.
OCT1, OAT1, and OAT3 are among the most important multi-specific drug transporters in the
body. The SLC22 family of transporters can be separated into OATs (organic anion
transporters), OCTs (organic cation transporters), OCTNs (organic zwitterion/carnitine
transporters), and other less characterized subgroups, with OATs and OCTs receiving the
majority of research interest.
Subjects
Affiliations
- College of Osteopathic Medicine, California Health Sciences University
- Department of Bioengineering, University of California San Diego
- Department of Biology, University of California San Diego
- Department of Medicine, Division of Hematology/Oncology, University of California San Diego
- Department of Pediatrics, University of California San Diego
- UF Scripps Research Institute Florida